不同雾化方式治疗婴幼儿哮喘急性发作临床研究

Clinical study on treatments of acute episode of asthma in infants with different nebulizer

目的:探讨治疗儿童哮喘,缓解支气管痉挛,迅速解除缺氧状态的方法,验证氧驱动雾化吸入法的疗效。方法:将在我科日间病房住院的147例婴幼儿哮喘患儿,随机分成治疗组81例,对照组66例。在综合治疗的基础上,治疗组采用氧驱动雾化装置+面罩吸入给药,对照组予以超声雾化吸入治疗,比较两种雾化方式的治疗效果。结果:治疗组喘憋、缺氧状态及肺部哮鸣音较对照组明显改善;总有效率治疗组87.6%,对照组71.2%,两组疗效比较差异有统计学意义(P<0.05)。结论:氧驱动雾化吸入是治疗婴幼儿哮喘安全有效、可靠的方法之一。

Objective：To evaluate the clinical effect of the therapy of nebulized oxygen inhalation on infants with asthma. Methods： 147 infants with asthma were randomized into a treatment group （81 cases） and a control group （66 cases）. The treatment group was given oxygen driving nebulizers. The control group was given ultrasonic atomizing inhalation. And the curative effects were compared and analyzed between the two groups. Results： The course of the treatment group was significant efficient than those in the control one. The decompensation, anoxia and asthma in the treatment group improved much better than in the control one （ P 〈 O. 05 ）. The clinical effect rates of treatment group and control group were 87.6 % and 71.2 % respectively. There was a significant difference between the treatment group and the control group. Conclusions： Nebulized oxygen driving inhalation is an effective and secure therapeutic approach for infants with asthma.