热应激对骨骼肌离心运动损伤的保护作用及机制被引量：7

Research on Protective Effect and Mechanism of Prior Heat Stress against Eccentric Contraction-induced Damage

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摘要观察预热应激对大鼠骨骼肌离心运动损伤是否具有保护作用,并对预热应激的保护作用机制进行探讨。结果发现,预热应激组大鼠离心运动后最大强直收缩力比正常组下降少且恢复快,CK在运动后即刻显著低于正常组,MDA显著低于正常组,热应激组大鼠热休克蛋白和抗氧化剂都升高,可能是热应激提供保护作用的机制;这些数据表明预热应激对大鼠骨骼肌离心运动损伤具有保护作用。 This paper was to investigate whether prior heat stress had protective in rats against eccentric contraction induced muscle damage, and discussed the mechanism of mechanism effect of prior heat stress. The result showed that after eccentric exercise prior heat stress groups gastroenemius maximum tetanic force decreased lower and got easier recovery than normal control group＇s, CK and MDA significantly lower than normal group＇s after exercise. Heat shock proteins and antioxidants of prior heat stress rats increased apparently, which may be the mechanism of protective effect of prior heat stress. These data indicated that prior heat stress in rats had protection on eccentric contraction - induced muscle damage.

作者高前进李爱君马新东周越王瑞元

机构地区石家庄学院体育系石家庄职业技术学院体育系清华大学体育部北京体育大学

出处《成都体育学院学报》 CSSCI 北大核心 2007年第2期86-91,共6页 Journal of Chengdu Sport University

基金国家自然科学基金(No.30170448)资助项目

关键词预热应激腓肠肌离心运动损伤保护作用 prior heat stress, gastrocnemius, eccentric exercise induced damage, protective effect

分类号 G804.2 [文化科学—运动人体科学]

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1E.Papp,G.Nardai,C.Soti,et al.Molecular chaperones,stress proteins and redox homeostasis.Bio Factors.2003,17:249-257.
2Keith A.Webster.Serine phosphorylation and suppression of apoptosis by the small heat shock protein αB -crystallin.Circ Res.2003,92:130-132.
3Diana A.Lepore,John V.Hurley,Alastair G.Stewart,et al.Prior heat stress improves survival of ischemic-perfused skeletal muscle in vivo.Muscle Nerve.2000,23:1847 -1855.
4Wilson YT,Lepore DA,Riccio M,et al.Mild hypothermia protects against ischemia -reperfusion injury in rabbrit skeletal muscle.Br J Plast Surg.1997,50:343 -348.
5Currie R.W.,Tanguay R.M.,Kingma Jr.J.G.Heatshock response and limitation of tissue necrosis during occlusion / resperfusion in rabbit hearts.Circulation.1993,87:963 -971.
6Armstrong RB.Eccentric exercise -induced injury to rat skeletal muscle.[J].Appl.Physio.1983,54:80 -93.
7侯曼.大白鼠腓肠肌被动拉伸的力学性质的研究[D].上海体育学院硕士论文,1985(5).
8McArdle ANNE,Wolfgang H.Dillmann,Ruben Mestril,et al.Overexpreasion of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction.FASEB.2003-12-19 Published online.
9Nikolaou PK,et al.Biomechanical and histological evaluation of muscle after controlled strain injury.Am.J.Sports Med.1987,15:9-12.
10Naito J,Hartung E,Schramm E,et al.Heat stress produces an early phase of protection against oxidative damage in human muscle.Acta Anaesthesiol Scand.1999,43(1):77 -81.