芝麻花黄酮类化学成分研究

Flavones from flowers of Sesamum indicum

目的:对芝麻花Sesamum indicum的化学成分进行研究。方法:运用硅胶柱色谱、凝胶柱色谱、反相柱色谱等多种色谱手段进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果:共得到6个黄酮类化合物,分别鉴定为芹菜素(1),鼬瓣花亭(ladanetin,2),鼬瓣花亭-6-O-β-D-葡萄糖苷(ladanetin-6-O-β-Dglucoside,3),芹菜素-7-O-葡糖醛酸(ap igen in-7-O-glucuron ic ac id,4),胡麻素(pedalitin,5),胡麻素-6-O-葡萄糖甙(pedalitin-6-O-glu-coside,6)。结论:6个黄酮化合物均为首次从该植物中分离得到。

Objective： To investigate the chemical constituents from flowers of Sesamurn indicum. Method： Column chromatography with silica gel, C18 and Sephadex LH -20 as packing materials was used to separate the chemical constituents, and the structures were determined by chemical and spectroscopic methods. Result： Six flavones were isolated and elucidated as apigenin （1）, ladanetin （2）, ladanetin-6-O-β-D-glucoside （3）, apigenin-7-O-glucuronic acid （4）, pedalitin （5）, and pedalitin-6-O-glucoside （6）. Conclusion： All of the compounds were isolated from this plant for the first time.