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多尼培南的药理和临床研究 被引量:4

Pharmacology and clinical evaluation of doripenem
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摘要 多尼培南(doripenem,S-4661)是新型碳青霉烯类抗生素,抗菌谱广,抗菌活性强,对多种G+和G-菌均有很强的抗菌活性。现对其作用机制、抗菌活性、药动学、临床应用及药物不良反应做一综述。 Doripenem (S-4661), a new 1-beta-methyl carbapenem, has a broad antibacterial spectrum against gram-positive and -negative bacteria. This review summarizes pharmacological mechanism, antibacterial potency, pharmacokinetics, clinical uses and side effects of doripenem
出处 《中国新药杂志》 CAS CSCD 北大核心 2007年第5期414-416,共3页 Chinese Journal of New Drugs
关键词 多尼培南 药理作用 临床研究 doripenem pharmacology clinical research
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参考文献15

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