C-fos与生殖细胞发育

C-fos and the Development of Reproductive Cell

原癌基因C-fos是即刻早期基因(immediate early gene,IEG),它的表达产物作为细胞内信号传递的第三信使(third messenger)对细胞增殖、分化、凋亡及信号转导具有重要生理作用。本文就C-fos分子结构、表达机制、对生殖发育、细胞凋亡的研究进行综述。

C-fos is an immediate early gene and its expressible protein plays some key roles in the cell division,cell differentiation and cell apoptosis as the third messenger in the massage transmission.The fields,including the molecular structure,expressible mechanism of the C-fos,and regulation in the development and cell apoptosis,are explicated in the article.