外周T细胞淋巴瘤的新亚型─组织细胞样T细胞淋巴瘤

A new subtype of peripheral T-cell lymphoma-histiocytoid T-cell lymphoma

报告６例外周Ｔ细胞淋巴瘤的新亚型－组织细胞样Ｔ细胞淋巴瘤。６例均发生于颈部淋巴结（其中颈右４例，颈左２例）。组织学上完全是组织细胞特点－细胞大，胞浆丰富，有吞噬。但免疫组化为Ｔ细胞表型（ＵＣＨＬ１（＋）），１例基因重排为ＴＣＲｒ（＋），证实为Ｔ细胞来源。

Six cases with a new subtype of peripheral T-cell lymphoma, histiocytoid T-cell lymphoma, were reported. The lymphoma occurred in cervical lymph nodes in all the cases (right in 4 and left in 2 cases).Histopathologically. the cells were large, rich in cytoplasm and capable of phagocytosis, but immunohistochemically, the cells had T-cell phenotype (UCHL1+).Gene rearrangement was TLCRr (+) in one case,demonstrating T-cell origin.