子宫外蜕膜结节的病理学观察

Pathological study of reseted ectopic decidua of extra-uterine

采用ＰＡＳ、波形蛋白（ｖｉｍｅｎｔｉｎ）、上皮膜抗原（ＥＭＡ）、雌激素抗体（ＥＲ）和孕酮抗体（ＰＲ），对３例卵巢蜕膜结节（其中２例伴有腹膜结节），进行了免疫组织化学染色和光镜观察。结果３例均表达波形蛋白，而上皮膜呈阴性，支持蜕膜样细胞来源于体腔上皮。雌激素受体和孕激素受体显强阳性。说明妊娠期间，雌激素和孕激素的大量存在对异位蜕膜的形成和生长具有决定性的作用。

Decidual reactions on the surface of ovary were confirmed in 3 cases, in whom 2 cases were accompanied by peritoneal nodes, by PAS staining and immunohistochemistry, including vimentin, epithelial membrane antigen (EMA), estrogen receptor (ER), progesterone receptor (PgR) stainings. Positive immunostaining for vimentin was found in all of these cases, but negative for EMA. Immunohistochemistry proved that decidual cells are originated from the coelom epithelium (Mullerian). Decidual cells were strongly positive for ER and PgR, showing that during pregnancy, the presence of large amount of estrogen and progesterone is of decisive action on the formation and development of ectopic decidua.