成人临床非典型性心肌炎的病原检测（PCR技术）及临床病理分析

Pathogen detection (PCR) and clinicopathological analysis of clinically atypical myocarditis in adult

本文报告４例尸解诊断为急性非化脓性心肌炎猝死病人，并运用ＰＣＲ技术进行病原学诊断，均为小ＲＮＡ病专用性。临床上不典型性表现为神经系统症状为主者，导致临床诊为颅内占位性病变；有呕吐、腹泻等消化道症状者，诊断为胃肠炎；也有以阑尾炎诊治者，实际上是严重的心肌坏死为主的炎症。本文目的在于提高临床对不典型心肌炎的诊断警惕性，用较先进、较敏感的ＰＣＲ方法进行病因检测，有利于不典型心肌炎的病因诊断。

cases of sudden death with acute non-pyogenic myocarditis were examined with polymerase chain reaction (PCR). The results revealed that all cases were positive for small RNA virus. One of the patients had some symptoms of nervous system, leading to the diagnosis as intracranial lesion. One who had vomiting and diarrhoea was diagnosed as gastrointestinal inflammation and treated as appendicitis. In fact, the disease was severe necrotic inflammation of myocardium. The purpose of this article is to demonstrate the importance of vigilance of clinically atypical myocarditis to clinical doctors. It is useful to detect pathogen with the sensitive PCR method.