冠脉药物涂层支架在冠心病的应用研究

Research on the effect of drug-eluting stent(DES) in the treatment of coronary artery disease(CAD)-with clinical analysis of 31 cases

目的:探讨雷帕霉素药物洗脱支架(CypherTm)在冠心病(CHD)冠状动脉介入治疗中应用的安全性和有效性。方法:以2004年5月至2005年5月在我科住院的31例植入雷帕酶素支架35枚的冠心病病人作为研究组,以1999年1月至2003年12月在我科住院的30例植入非药物支架的冠心病病人作为对照组。结果:研究组与对照组支架置入的成功率均为100%。研究组一年后再狭窄率0%,对照组一年后再狭窄率13.3%。结论:经皮冠状动脉内支架植入治疗安全可行、疗效确切,药物洗脱支架对防止再狭窄有独到之处。

Objectives： To evaluate the clinical safety and effectiveness of Drug-Eluting Stent （DES） -Cypher in the treatment of Cronary Artery Diseases （CAD）. Method： In the test group, 31 patients underwent DES with 35 stents from May 2004 to May 2005, the other 30 of the control group received non-DEC from January 1999 to December 2003. Result： Both groups showed a success rate of 100% in stenting. In follow-up （ 12 months） none was detected with restenosis in the test group while 13.3% of the control group was positive. Conclusion： PCI treatment sis safe and effective. DES is identical in the preventing of restenosis.