摘要
目的:测定盐酸吡格列酮片的含量。方法:以0.1 mol·L^(-1)盐酸为溶剂,用紫外分光光度法在269 nm的波长处测定。结果:溶液浓度在2.44～48.72μg·ml^(-1)的浓度范围内有良好的线性关系,r=1.0000(n=8)。平均回收率102.5%,RSD= 2.0%。结论:该方法简便、稳定性好、结果准确可靠,可用于药品制剂的质量控制。
Objective： To establish the content determination method for determination the content of pioglitazone hydrochloride tablets. Method： UV spectrophotometry was used with 0.1 mol· L^- 1 hydrochloric acid solution as solvent and detection wavelength was at 269 nm. Result： The linear range of pioglitazone hydrochloride was 2, 44 -48, 72 μg· ml^- 1 （r = 1. 000 0 ）, the average recovery was 102.5% with RSD 2.0%. Conclusion ： The method is simple and accurate. It can be used for quality control of pioglitazone hydrochloride tablets.
出处
《中国药师》
CAS
2007年第4期354-355,共2页
China Pharmacist
关键词
盐酸吡格列酮片
含量测定
紫外分光光度法
Pioglitazone hydrochloride
Contents determination
UV spectrophotometer
