早期应用尼莫通治疗外伤性脑内血肿的疗效研究

Effect of early application of nimotop on traumatic intracerebral hematoma

目的:探讨早期应用尼莫通治疗外伤性脑内血肿的临床疗效。方法:对我院收治的41例外伤性脑内血肿病人于入院/术后48h应用尼莫通治疗,并进行随机对照研究。结果:住院期间治疗组41例,死亡8例(20%);对照组41例,死亡12例(29%),两组病死率比较差异无显著性(P>0.05)。获得随访者以ADL分级标准评定,治疗组33例,良好生存26例(79%);对照组29例,良好生存15例(52%),两组良好生存率比较差异有显著性(P<0.05)。结论:早期合理应用尼莫通治疗外伤性脑内血肿可提高生存质量,改善预后。

Objective To investigate the curative effects of early application of nimotop on traumatic intraeerebral hematoma. Methods Eighty-two patients of traumatic intraeerebral hematoma were divided randomly into two groups, including control group （n=41） and therapy group （n=41）. Therapy group used nimotop at 48 hours after hospitalization or surgery. Results During the hospital stay, 8 cases （8/41, 20%） died in therapy group, while 12 eases（ 12/41, 29%） died in control group. The fatality rate of both groups showed no signifieanee（P 〉 0.05）. According to survival＇s judgement of ADL graded standard, 26 eases（26/33, 79%） were well-survival in therapy group and 15 eases（15/29, 52%） in control group. The well-survival rate of both groups showed signifieanee（P 〈 0.05）. Conclusion Nimotop rationally and early applied to the traumatic intraeerebral hematoma is able to raise quality of survival and to improve prognosis.