色素上皮衍生因子与眼血管增生性疾病
摘要
色素上皮衍生因子（pigment epithelium derived factor，PEDF）是一类分子量为50000的糖蛋白，1989年在胎儿视网膜色素上皮（retinal pigment epithelium，RPE）细胞的条件培养基中首次发现并以此命名，以后逐渐被发现具有非常重要的神经营养和保护作用。新生血管生成是眼部疾病的常见并发症，近年来发现PEDF是眼组织中最有效的内源性血管生成抑制剂，成为治疗眼部血管增生性疾病研究的热点。
出处
《中华围产医学杂志》
CAS
2007年第2期133-135,共3页
Chinese Journal of Perinatal Medicine
基金
广东省自然科学基金资助（032432）
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