阿洛西林中高分子杂质的分离测定

Isolation and determination of high molecular weight impurities in azlocillin

采用葡聚糖凝胶Ｇ－１０凝胶色谱及２１０ｎｍ紫外分光光度法分离测定阿洛西林中高分子杂质的含量，方法快速简便，亦可用于其它β－内酰胺类抗生素中高分子杂质的测定。

Isolation and determination of azlocillin high molecular weight impurities using sephadex G-10 gel column chromatography followed by spectrophometry at 210nm was established.The method was rapid, simple and convenient. High molecular weight impurities in other penicillin's(or β-lactam antibiotics)were also determined by this method.