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生物组织电穿孔中的热效应研究 被引量:1

STUDY ON THE THERMAL EFFECTS OF BIOLOGICAL TISSUES DURING ELECTROPORATION
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摘要 本文对生物组织电穿孔中的热效应问题进行了计算研究。结果表明生物组织电穿孔过程中,选用不当的脉冲电压参数,会对组织造成严重的热损伤。若采用相同的烧伤阈值来描述热损伤范围,则相同电脉冲参数条件下在体组织比离体组织受到的热损伤更大。 In this article, the thermal effects of biological tissues during electroporation were studied through numerical simulations. It was indicated that the biological tissues would be thermally injured during electroporation if inappropriate parameters of pulse voltage were administrated. The result also suggested that under the same parameter of pulse voltage and the same burn threshold for description of thermal injury degree, the tissue in vivo is liable to be thermally injured, compared with the tissue in vitro.
作者 邓中山 刘静
出处 《工程热物理学报》 EI CAS CSCD 北大核心 2006年第1期118-120,共3页 Journal of Engineering Thermophysics
基金 国家自然科学基金资助项目(No.50306027)
关键词 生物组织 电穿孔 热效应 热损伤 biological tissue electroporation thermal effect thermal injury
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参考文献8

  • 1Gehl J.Electroporation:Theory and Methods,Perspectives for Drug Delivery,Gene Therapy and Research.Acta Physiologica Scandinavica,2003,177(4):437-447
  • 2Shirakashi R,Kostner C M,Muller K J,et,al.Intracellar Delivery of Trehalose into Mammalian Cells by Electropermeabilization.Journal of Membrane Biology,2002,189(1):45-54
  • 3Pliquett U F,Martin G T,Weaver J C.Kinetics of the Temperature Rise within Human Stratum Corneum During Electroporation and Iontophoresis.Bioelectrochemistry,2002,57(1):65-72
  • 4Martin G T,Pliquett U F,Weaver J C.Theoretical Analysis of Localized Hheating in Human Skin Subjected to High Voltage Pulses.Bioelectrochemistry,2002,57(1):55-64
  • 5Davalos R V,Rubinsky B,Mir L M.Theoretical Analysis of the Thermal Effects During in Vivo Tissue Electroporation.Bioelectrochemistry,2003,61(1-2):99-107
  • 6Deng Z S,Liu J.Monte Carlo Method to Solve MultiDimensional Bioheat Transfer Problem.Numerical Heat Transfer,Part B:Fundamentals,2002,42(6):543-567
  • 7Boone K,Barber D,Brown B.Review-Imaging with Electricity:Report of the European Concerted Action on Impedance Tomography.Journal of Medical Engineering and Technology,1997,21(6):201-232
  • 8Davalos RV,Huang Y,Rubinsky B.Electroporation:BioElectrochemical Mass Transfer at the Nano Scale.Microscale Thermophysical Engineering,2000,4(3):147-159

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