超广谱β-内酰胺酶研究进展

Progress in extended-spectrum β-lactamases

本文介绍关于超广谱β-内酰胺酶（ESBL）的分类、流行病学、治疗及传播控制等方面的研究进展。近年来，产ESBL菌株逐年增多，关于治疗产ESBL菌的抗生素选择众说纷纭，有认为碳青霉烯类是唯一有效的药物，也有主张选用其它药物。本文重点介绍应用第三、四代头孢菌素的临床评价。

This article introduces progress in the classificatioin,epidemiology,treatment and control of dissemination about extended-spectrum beta-lactamases （ESBL）. In recent years, the quantity of bacterial producing ESBL has increased more and more, and it is disputed on how to treat the infection caused by produced bacterial producing ESBL. Some consider carbapenems are the only effective medicines,while some prefer to other medicines. The article mainly introduces clinical appraisal of applying third, fourth generation cephalosporin.