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聚乙二醇支载1,2,3-三唑化合物的合成 被引量：1

Poly(ethylene glycol) supported synthesis of triazoles
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摘要 以聚乙二醇作为可溶性聚合物载体,得到了聚乙二醇支载的的邻叠氮苯甲酸酯,与炔酯发生1,3-偶极环加成反应后,以KCN作为解脱剂,从聚乙二醇上解脱得到1,2,3-三唑化合物,具有较好的产率,经红外、核磁及元素分析等检测,所得数据与其结构相符. An efficient method to synthesize 1, 2, 3-trizoles has been developed using poly （ethylene glycol） as soluble polymer support. Poly （ethylene glycol） （PEG） stepwise reacted with oazidobenzoic acid ester, acetylenie ester to produce the corresponding PEG-bound 1, 2, 3-trizoles through 1, 3-dipolar cycloaddition. After cleavage from the polymer in the presence of KCN and methanol, afforded 1, 2, 3-trizole derivatives in good yields molecule was detected by IR, H^1 NMR, C^13 NMR and EA.
作者 黄艳玲 彭红丹 陈祖兴 杨桂春
机构地区 湖北大学化学化工学院
出处 《湖北大学学报（自然科学版）》 CAS 北大核心 2007年第1期72-74,共3页 Journal of Hubei University：Natural Science
基金 湖北省教育厅科研项目(No:2001A1017 2004D008)资助
关键词 聚乙二醇 支载 合成 1 2 3-三唑 poly（ethylene glycol） support synthesis 1,2,3-triazoles
分类号 O626.26 [理学—有机化学]
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参考文献9

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同被引文献21

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湖北大学学报（自然科学版）
2007年 第1期

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