癫痫中医证候相关因素调查

Study on Relevant Factors of TCM Syndromes of Epilepsy

目的找出癫痫中医证候分布特点和主要趋势,为中西医结合治疗开阔思路。方法制定临床病例观察资料,探究中医证候与本病相关因素的关系。结果202例患者各证候之间性别、发作频率、病因、影像学检查及脑电图严重程度比较差异无统计学意义(P>0.05)。脾虚痰盛证以少年儿童多见,肝肾阴虚证以中老年多见,差异有显著统计学意义(P<0.01)。不同证候的病程、发病年龄、发作类型、放电起源部位差异有统计学意义(P<0.05)。结论癫痫中医证候以风痰内阻证及痰火上扰证多见。各证候在性别、发作频率、病因、影像学检查及脑电图严重程度等方面无特异性。脾虚痰盛证以少年儿童多见;肝肾阴虚证以中老年多见。病程长以虚证或虚实夹杂证多见;病程短以实证多见。发病于儿童期以虚实夹杂证或虚证多见;发病于青年、中年时期以实证较多见。放电部位起源于颞叶者以风痰内阻证多见,起源于额叶者以痰火上扰证多见,全面性放电以脾虚痰盛证多见。

Objetcive To find out the rules of distribution of TCM syndromes and the main trend in epilepsy, and search a new way of integration of TCM and western medicine in treatment of epilepsy. Methods A scale for observation was formulated and the influences of relevant factors on TCM syndromes were studied. Results All TCM syndromes had no statistical significance differences （P〉0.05） in sex, attack frequency, cause of disease, MRI and EEG among202 patients. The TCM syndrome of weak in spleen and phlegm excess was the main type of child patients, while deficiency in liver and kidney was common in middle-aged and old patients, and they had prominent statistical significance （P 〈0.01）. Course of disease, onset age, different types, different discharge locations had statistical significance （P〈0.05） in different syndromes. Conclusions Most important two TCM syndrom types are wind phlegm and phlegm fire disturbing upper body in epilepsy. All TCM syndromes have no statistical significance （P〉0.05） in sex, attack frequency, cause of disease, MRI and EEG. The weak in spleen and phlegm excess type is common in children＇ and the deficiency in liver and kidney type is usual in middle-aged and the elderly. Long disease course manifests deficiency or deficiency mixed with excess syndromes, while short course mainly shows excess syndromes. Earlier age of onset manifests deficiency or deficiency mixed with excess syndromes, and onset in youth and middle age often show excess syndromes. Discharge location in temporal lobe is often of wind phlegm type, while discharge location in frontal lobe often belongs to phlegm fire disturbing upper body type. Weak in spleen and phlegm excess type often can be seen in general discharge.