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调节正常T细胞表达和分泌的细胞因子与肾脏疾病

Relationship between Regulated upon Activation Normal T Cell Expressed and Secreted Factor and Kidney Disease
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摘要 调节正常T细胞表达和分泌的细胞因子(RANTES)是β-趋化性细胞因子家族,在肾脏炎症发展过程中可趋化炎症细胞浸润,还可激活淋巴细胞,扩大炎症。在肾小球肾病、移植后肾病、糖尿病肾病中均发现RANTES表达增高,且其及其受体基因多态性也与肾脏疾病发生有密切关系。阻断RANTES信号途径为治疗肾脏疾病提供了一个新的前景。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2007年第5期383-386,共4页 Journal of Applied Clinical Pediatrics
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