1Greenwood K, Butt AM. Evidence that perinatal and adult NG2-glia are not conventional oligodendrocyte progenitors and do not depend on axons for their survival. Mol Cell Neurosci, 2003,23: 544-558.
2Sasaki R, Matsumoto A, Itoh K, et al. Target cells of apoptosis in the adult murine dentate gyrus and O4 immunoreactivity after ionizing radiation. Neurosci Letters, 2000,279: 57-60.
3Sano K, Morii K, Sato M, et al. Radiation-induced diffuse brain injury in the neonatal rat model-radiation-induced apoptosis of oligodendrocytes.Neurol Med Chir, 2000,40: 495-500.
4Lees GJ, Leong W. Differential effects of NBQX on the distal and local toxicity of glutamate agonists administered intra-hippocampally. Brain Res, 1993,19:1-7.
5Baumann N, Dinh DP. Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiol Rev,2001,81:871-927.
6McDonald JW, Althomsons SP, Hyrc KL, et al. Oligodendrocyte from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotxicity. Nat Med, 1998,4:291-297.
7Massieu L,Tapia R.2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo. Neuroscience, 1994,59: 931-938.
8Tofilon PJ, Fike JR. The radioresponse of the central nervous system: a dynamic process. Radiat Res,2000,153:357-370.
9Belka C, Budach W, Kortmann RD, et al. Radiation induced CNS toxicity-molecular and cellular mechanisms. Br J Cancer, 2001,85: 1233-1239.
6Stupp R, Mason WP, Vanden Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma[J]. N Engl J Med,2005,352(10):987-996.
7Athanassiou H, Synodinou M, Maragoudakis E, et al. Randomized phase Ⅱ study of t emozolomide and radio- therapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme[J]. J Clin Oncol, 2005,23(10) : 2372-2377.
8Hegi ME,Diserens AC,Gorlia T,et al. MGMT gene silencing and benefit from temozolomide in glioblastoma [J]. N Engl J Med,2005,352(10) :997-1003.
9Mutter N, Stupp R. Temozolomide: a milestone in neurooncology and beyond [J]? Expert Rev Anticancer Ther, 2006,6 (8) : 1187-1204.
10Stupp R,Mason WP,van den Bent MJ,et al.Radiotherapy plus concomitant and adjuvant temozolomide for gtioblastoma[J].N Engt J Med,2005,352(10):987-996.