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血浆N末端原脑钠肽水平在心力衰竭患者诊断中的应用的研究

THE STUDY OF N-TERMINA-PRO-BRAIN MATRIURETIC PERTIDE IN DIAGNOSIS OF HEART FAILURE
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摘要 目的探讨N末端原脑钠肽(NT-proBNP)在心力衰竭患者诊断中的应用。方法选择慢性心力衰竭患者71例,以纽约心脏病心功能分级(NYHA分级)评定心功能,采取双抗体夹心酶联免疫法吸附(ELISA)法测定NT-proBNP水平,同时选择心功能I级的患者60例作为对照。结果Nt-proBNP水平在心力衰竭组(1612.9fmol/mL)明显高于对照组(430.2fmol/mL)且随心功能分级的增加,其水平增高(p<0.01)结论NT-proBNP水平在心力衰患者中明显升高,可做为诊断心衰的一项生化指标。 Objective To Studv the Value of NT - proBNP in the diagnosis of heart failure. Methods：Sevonty one sufferer of heart failure and to healthy persons were selected. And NT - proBNP was measured in all of the patients by enzyme - linked immunosorbent assay （ELISA）. Results：Concentration of NT - proBNP showel significent difference tetween sufferer and tealthy peraons. The level of NT - proBNP was higher in the group of heart failure sufferer than it was in the contrast group. Conclusicn：NT - proBNP was a good index in the diagnosis of heart failure.
作者 游陆 王宇辉 赵莹
机构地区 牡丹江医学院附属红旗医院
出处 《牡丹江医学院学报》 2007年第1期7-9,共3页 Journal of Mudanjiang Medical University
关键词 心力衰竭 利钠肽 脑 诊斯 heart failure. Natriuretic peptide, brain, diagnosis
分类号 R55 [医药卫生—血液循环系统疾病]
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参考文献8

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二级参考文献17

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2007年 第1期

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