肾脏血流阻力指数对实验性单侧输尿管部分梗阻的诊断价值

The diagnostic value of renal blood flow resistive index for experi mental unilateral partial ureter obstruction

目的判断肾脏血流阻力指数(RI)对实验性单侧输尿管部分梗阻的诊断价值。方法40只成年大白兔制作成单侧输尿管部分梗阻模型,应用彩色多普勒超声仪在术前、术后1、2、4、8周随机测量10只动物的双侧肾脏RI,并计算双侧RI的差值(△RI)和比率(RIR)。以RI≥0.7,△RI≥0.1,RIR≥1.10为标准计算其诊断梗阻的准确性。结果随着梗阻时间的延长,RI进行性升高,RI,△RI和RIR诊断梗阻的准确性依次提高。结论梗阻发生后RI是一个时间相关性的生理参数,比较双侧肾脏的RI值可显著提高其诊断梗阻的准确性。

Objective： To assess the diagnostic values of renal resistive index （RI） for obstructive uropathy in adult rabbits with unilateral partial ureteral obstruction.Methods：40 rabbits were operated as partial obstruction of right ureter. The RI of obstructed and contralateral kidneys were measured by Doppier sonography preoperatively and postoperatively at 1, 2, 4 and 8 weeks, respectively, then calculated the delta RI and RI ratio for each animal, the accuracy for each was judged according to the standard of RI≥0.7 ,△RI≥0.1, RIR≥ 1.10. Results： RI was progressively increased over obstructive time, the diagnostic effieieney of RI, delta RI and RI ratio for obstruction was elevated one by one. Conclusion： RI is a time-dependent physiological parameters, it can significantly enchance the diagnostic value for obstructive uropathy by analysis of the interrenal RI difference or ratio.