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骨桥蛋白与乳腺癌的关系及其影像学表现

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摘要 骨桥蛋白(osteopontion,OPN)是一种有多种功能的分泌型磷酸化糖蛋白。1979年,Senger最早在骨组织发现并提取,是骨组织细胞外基质的主要成分之一,参与骨的矿化与吸收。OPN广泛分布于人体组织和细胞。近年来,大量研究显示,OPN作为一种恶性转化的分泌性细胞因子,参与了多种肿瘤的发生、发展、转移及预后。本文简要介绍了OPN与乳腺癌的关系。
作者 杨光 张祥宏
出处 《中国医学影像学杂志》 CSCD 2007年第2期142-144,共3页 Chinese Journal of Medical Imaging
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参考文献25

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