2Maina F,Hilton MC,Andres R.Multiple roles for hepatocyte growth factor in sympathetic neuron development[J].Neuron,1998,20(5):835-846.
3Ebens A,Brose K,Leonardo ED,et al.Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons[J].Neuron,1996,17(6):1157-1172.
4Hayashi T,Abe K,Sakurai M,et al.Inductions of hepatocyte growth factor and its activator in rat brain with permanent middle cerebral artery occlusion[J].Brain Res,1998,799:311-316.
6Zhang L,Himi T,Morita I,et al.Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway[J].J Neurosci Res,2000,59(4):489-496.
7HossainMA,Russell JC,Gomez R,et al.Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase / akt-dependent and MAPK/CREB-independent[J].J Neurochem,2002,81:365-378.
8Hayashi K,Morishita R,Nakagami H,et al.Gene therapy for preventing neuronal death using hepatocyte growth factor:in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons[J].Gene Ther,2001,8(15):1167-1173.
9Shimamura M,Sato N,Oshima K,et al.Novel therapeutic strategy to treat brain ischemia:Overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model[J].Circulation,2004,109:424-431.
2Shimamura M, Sato N, Oshima K, et al. Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model. Circulation, 2004,109(3):424～431.
3Hayashi K, Morishita R, Nakagami H, et al. Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons. Gene Ther, 2001,8(1
4Hayashi T, Abe K, Sakurai M, et al. Inductions of hepatocyte growth factor and its activator in rat brain with permanent middle cerebral artery occlusion. Brain Res, 1998,799(2):311-6222
5Carmelier P. Mechanisms of angiogenesis and arteriogenesis. Nat Med,2000,6:389-395
6Emanueli C,Madeddu P. Angiogenesis gene therapy to rescue ischemic tissues: achievements and future direction. Br J Pharmacol,2001,133:951-958
7suzuki N, Miyazawa T, Matsumoto K. Hepatocyte growth factor reduces the infarct volume after cerebral ischemia in rats. Neurol Res, 2001, 23(4):417-424
