期刊文献+

成体心肌干细胞的研究进展 被引量:2

The research progress about adult cardiac stem cells
下载PDF
导出
摘要 近来的研究表明无论在正常还是病理情况下心室肌细胞中均存在处于分裂周期的细胞,即成体心脏内存在具有特异性心肌分化潜能的多能干细胞———成体心肌干细胞。本文综述了成体心肌干细胞的发现、特征、功能和目前研究中仍存在的问题与展望。 In resent investigates, several researchers have found that there are some cells being in cell division cycle whether in normal or pathological ventricle cardiomyocyte. That is to say, some kind of muhi-functional stem cells exist in the adult heart of person or animal, we call them cardiac stem cells. Cardiac stem cells have the special ability of differentiating to myocardium cells, smooth muscle cells, vascular endothelial cells. In this summary, we overview the discovery, characters, functions, possible problems in future researches and prospect of the adult cardiac stem cells.
作者 李妍 陆东风
出处 《国际内科学杂志》 CAS 2007年第3期174-176,F0003,共4页 International Journal of Internal Medicine
基金 广州医学院科研项目立项 编号(2006ZR009)
关键词 成体心肌干细胞 心肌梗死 心肌再生 Adult cardiac stem cells Myocardial infarction Myocardial regeneration
  • 相关文献

参考文献18

  • 1Beltrami AP,Urbanek K,Kajstura J,et al.Evidence that human cardiac myocytes divide after myocardial infarction.N Engl J Med,2001,344(23):1750-1757.
  • 2Nadal-Ginard B,Anversa P,Kajstura J,et al.Cardiac stem cells and myocardial regeneration.Novartis Found Symp,2005,265:142-154.
  • 3Anversa P,Kajstura J,Leri A,et al.Life and death of cardiac stem cells a paradigm shift in cardiac biology.Circulation,2006,113(11):1451-1463.
  • 4Beltrami AP,Barlucchi L,Torella D,et aL Adult cardiac stem cells are multipotent and support myocardial regeneration.Cell,2003,114 (6):763-776.
  • 5Laflamme MA,Myerson D,Saffitz JE,et al.Evidence for cardio-myocyte repopulation by extracardiac progenitors in transplanted human hearts.Circ Res,2002,90 (6):634-640.
  • 6Laugwitz KL,Moretti A,Lam J,et al.Postnatal isll+ cadioblasts enter fully differentiated cardiomyocyte lineages.Nature,2005,433(7026):647-653.
  • 7Oh H,Bradfute SB,Gallardo TD,et al.Cardiac progenitor cells from adult myocardium:homing,differentiation,and fusion after infarction.Proc Natl Acad Sci U S A,2003,100 (21):12313-12318.
  • 8Smith RR,Abraham R,Messina E,et al.Isolation,expansion,and characterization of cardiac stem cells from endomyocardial biopsies.Circulation,2005,111 (13):1720-1721.
  • 9Messina E,De Angelis L,Frati G,et al.Electrophysiology of human and porcine adult cardiac stem cells isolated from endomyocardial biopsies; late-breaking developments in stem cell biology and cardiac growth regulation.Circ Res,2004,95(9):911-921.
  • 10Dawn B,Stein AB,Urbanek K,et al.Isolation and expansion of adult cardiac stem cells from human and murine heart.Proc Natl Acad Sci U S A,2005,102(10):3766-3771.

同被引文献83

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部