糖尿病并发脑梗死的病理生理学

The Pathophysiology of Cerebral Infarction in Diabetes

研究发现，糖尿病患者的脑梗死发病率显著增高且预后更差。然而，糖尿病患者的卒中危险因素极为复杂。文章从葡萄糖和脂质代谢紊乱、高血压、胰岛素抵抗和高胰岛素血症、血管舒缩功能障碍、脂联素和黏附分子表达的改变以及基因多态性等方面对该领域的研究进展进行了综述。

Studies have found that the incidence of cerebral infarction in patients with diabetes mellitus increases significantly, and their prognosis is worse. However, the risk factors in patients with diabetes mellitus are most complicated, qqais article reviews the recent progresses in this field from the aspects of glucose and lipid metabolic disturbances, hypertension, insulin resistance and hyperinsulinemia, vasomotor function abnormality, changes of adiponectin and adhesion molecule expression, as well as gene polymorphism.