五子衍宗方的临床运用及现代研究

Review on Clinical Application and Current Research of Wuzi Yanzong Prescription

目的:综述近年来五子衍宗方的临床运用、药理、质控等研究概况。方法:对10余年来该方的临床运用和药理研究文献进行了回顾和总结。结果:该方现代临床用于治疗生殖泌尿、内科及抗衰老、轻度认知障碍等多种疾病;药理研究表明具有提高生殖器官重量、增加雄性激素分泌,降低血糖,提高机体免疫功能,抗衰老及增强学习记忆能力等作用,长期毒性研究证实安全无毒;初步建立五子衍宗丸质量控制标准。结论:五子衍宗方具有多种临床用途,其中促进学习记忆的作用机制仍需进一步研究。

Objective：To Summarize the general state of clinical application, pharmacological and quality control research on Wuzi Yanzong prescription in recent years. Methods：The clinic and research literatures about this prescription were summarized. Results： Now its application is expanding to treat procreation and urinary systematic diseases, internal diseases,anti-senility and mild cognitive impairment and some other diseases. Pharmacological research showed it can increase weight of reproductive organs, enhance male hormone secretion, lower content of blood sugar, strengthen body immune function, antagonize aging and improve learning and memory ability. Long-term toxicity research proved that the prescription was safe and innocuous for oral taking, and the standard of quality control of this prescription has been primarily established. Conclusion： Wuzi Yanzong prescription has been used to cure many diseases and the mechanism of good nootropic effects needs further investigated.