女性小儿单纯性肥胖症患者血清脂联素与胰岛素水平相关性分析

Study on the Relationship Between the Serum Adiponectin and Insulin Levels in Female Children with Simple Obesity

目的:探讨了女性小儿肥胖症患者血清脂联素和胰岛素水平的相关性。方法:采用放射免疫分析对32例女性小儿单纯性肥胖症患者进行了血清脂联素和胰岛素测定,并以35名正常健康女孩为对照。结果:女性小儿单纯性肥胖症患者血清脂联素水平非常显著地低于正常儿(P<0.01),血清胰岛素水平则显著高于正常儿(P<0.01),两者呈明显的负相关。结论:女性小儿单纯性肥胖症患者血清脂联素和胰岛素水平密切相关,对判断病情的严重程度、病情的发展均具有重要的临床价值。

Objective To study the relationship between the serum adiponectin and insulin levels in female children with simple obesity. Methods Levels of serum adiponectin and insulin were detected with RIA in 32 female children with simple obesity and 35 controls. Results In the patients, the serum adiponectin levels were significantly lower than those in controls （P 〈 0.01 ）, while the serum insulin levels were significantly higher （ P 〈 0.01 ）. Serum adiponectin and insulin levels were mutually negatively correlate. Conclusion There is a close relationship between the serum adiponectin and insulin levels in children with simple obesity.