摘要
α-羟基乙酸是一种重要的大宗精细化工中间体,广泛应用于黏合剂、金属清洗、生物降解材料、染色、纺织,而且是个人护理产品的重要组成成分。化学法生产羟基乙酸存在原料消耗大、产品收率低、环境污染严重等缺点;生物法合成羟基乙酸条件温和、底物转化率高,为绿色合成羟基乙酸提供强有力的技术支持。文章比较了各种羟基乙酸定性及定量分析方法,综述了羟基乙酸分离方法,特别是溶剂萃取和协同萃取效应。最后,分析了羟基乙酸的开发前景。
α-hydroxyacetic acid is one of the most important bulk fine chemicals, extensively used in adhesives, metal cleaning, biodegradable polymers, dyeing, textiles, and as a component in personal care products. The advantages of α-hydroxyacetic acid biosynthesis over traditional chemical conversion are wide range of reaction condition, high conversion ratio and green process. The review highlights the technical developments in the identification, quantification and separation of a-hydroxyacetic acid, especially solvent extraction and synergistic extraction. Finally, the developmental prospect of a-hydroxyacetic acid is presented.
出处
《化工进展》
EI
CAS
CSCD
北大核心
2007年第4期496-500,共5页
Chemical Industry and Engineering Progress
基金
国家重大基础研究发展规划(No.2003CB716005)
浙江省科技厅项目(No.2005C31021)
关键词
羟基乙酸
腈水解酶
定量分析
协同萃取
hydroxyacetic acid
nitrilase
quantitative analysis
synergistic extraction
