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缺血预处理在肝脏外科中的应用

Clinical application of ischemic preconditioning in liver surgery and transplantation
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摘要 近年来缺血预处理已经从动物实验阶段走向临床应用,但其如何保护肝脏拮抗热缺血再灌注损伤或移植肝在保存过程中冷缺血损伤的机制还未完全明确,在肝脏外科临床的应用中也还存在不同观点。文中就缺血预处理在肝脏外科临床中的应用情况作一综述。 In recent years, the strategies of ischemic preconditioning have been developed from animal experiments to clinical application. However, little is known about the mechanisms of protective effect on for remnant liver against warm IR injury after partial hepatectomy or for grafts against cold storage injury. It is still a controversial issue in clinical application of ischemic preconditioning in liver surgery. In this review,we summaries the situation of ischemic preconditioning in liver surgery and transplantation.
作者 吴龙 钱叶本
出处 《国际外科学杂志》 2007年第4期270-274,共5页 International Journal of Surgery
关键词 缺血预处理 肝切除术 肝移植 缺血再灌注 ischemic preconditioning hepatectomy liver transplantation ischemia reperfusion
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