黄芩中黄芩苷浸取工艺优化

The Optimum Condition on Baicalin Extraction from Scutellaria baicalensis

目的:优选黄芩中黄芩苷的浸取工艺。方法:采用正交设计试验,以黄芩苷浸取率为指标,对影响黄芩中黄芩苷浸取工艺的因素进行了考察,比较了乙醇回流法与水煎煮法、超声波法、半仿生法的黄芩苷浸取率。结果:在浸取温度为80℃,浸取时间为1 h,乙醇浓度为60%,搅拌速度为400 r/min时,黄芩苷的浸取率最高,达83.09%。同时,结果表明,乙醇回流法在黄芩苷的浸取中优于其它的方法。结论:醇提法浸取效率高,经济,浸取剂利于回收,适合工业化生产。

Objective： To optimize the extraction process of baicalin from Scutellaria Baicalensis Georgi with ethanol. Methods： The extraction process of baicalin from Scutellaria Baicalensis Georgi was optimized with the aid of orthogonal experiments. Results： The optimal parameters were obtained as follows ： extracting temperature, extracting time, ethanol concentration and mechanical stirring speed were 80℃ ,1h, 60% and 400 r/min, respectively. The extracting rate of baicalin was 83.90%. Conclusion： Comparing ethanol circumfluence, boiling water, ultrasonic wave and semi-bionic on extracting baicalin from Scutellaria baicalensis Georgi, the ethanol circumfluence extraction is better than other technological conditions on extracting baicalin.