高原脑水肿现场就地急救治疗的效果及影响因素

Efficacy and influencing factors of emergency treatment on the spot for patients with high altitude cerebral edema

目的:探讨高原脑水肿就地急救治疗的效果和影响因素。方法:通过对50年住院病例的回顾性调查,分析高原脑水肿高原现场治疗的效果,寻找影响治疗效果的主要因素。结果:328例高原脑水肿患者经过就地治疗,319例治愈,治愈率达到97.3%,平均住院7.1 d。影响治疗效果的主要因素是多脏器功能障碍,占67%,其中56%患者伴有肺水肿,41%伴肾功能不全,14%伴心功能不全,3个以上脏器同时受损占12.5%。结论:高原脑水肿就地治疗是提高治愈率的重要措施,高原脑水肿并发多脏器功能障碍是影响治疗效果的主要因素。

Objective： to investigate the treatment method and pathogenic mechanism of acute high altitude cerebral edema, and evaluate the efficacy of emergencytreatment on the spot in high altitude regions. Methods： A total of 328 hospitalized patients with high altitude cerebral edema in the past 50 years were reviewed, the efficacy of emergency treatment on the spots was evaluated, and the factors influencing therapeutic effect were analyzed. Results： After emergency treatment on the spot for 328 patients with acute high altitude cerebral edema, 319 （97.3%） patients were successfully cured, and the average length of stay in hospital was 7.1 days. The leading factor influencing therapeutic effect was multiple organ dysfunction syndrome （MODS）. In those patients with MODS, 56 % had high altitude pulmonary edema, 41% had renal insufficiency, 14% had cardiac insufficiency, and 12.5% had three- organ dysfunction. Conclusion： Emerg critical for the treatment of high altitude cerebral edema, and ency treatment on the spot in high altitude regions is MODS was the main factor influencing therapeutic effect.