老年2型糖尿病下肢血管病变形态学特点

Morphological characteristics of lower extremity vascular diseases in elderly patients Type 2 Diabetes Mellitus

目的:探讨老年2型糖尿病患者下肢血管变的形态学特点。方法:采用彩色多普勒超声检测100例老年2型糖尿病患者(老年组)和87例非老年2型糖尿病患者(对照组)的下肢动脉,记录病程、糖尿病肾病(DN)、糖尿病视网模病变(DR)、冠心病(DHD)、脑血管病变(CVD),测血压、身高、体重,检测血生化标准。结果:老年组下肢血管病变检出率(93.0%)明显高于对照组(73.56%),P<0.01;下肢血管内膜-中层厚度增加检出率老年组(56.87%)明显高于对照组(29.12%),P<0.01;内膜-中层厚度增加,两组均呈节段性,其中老年组(42.52%)及对照组(40.13%)呈非均匀性;非同心圆性改变,组间比较差别无统计学意义。结论:老年2型糖尿病下肢血管病变发生率高,近半数为非均匀性、非同心圆性改变。

Objective：To investigate morphological characteristics of lower extremit diseases（LEVD）in elderly Patients were different from those in adults. Methods： Lower extremity arteries in 100 elderly patients with T2DM（elderly group） and 87 non- elderly patients with T2DM（ control group）were determines by color Doppler Uitrasonics. Coues of diseases, diabetic nephoropathy（ DH）, diabetic retinopthy（ DR）, coronary heart diseases（ GIID）, cerebrovascular diseases（ CVD）, blood pressure （Bp）, stature, body weight , the blood biochemical examination were recorded and compared. Results： The incidence of LEVI） in elderlygroup（93.0%）was significantly higher than in control group （73.56% ）（ P 〈 0.01）. The increase rate of lover extremity arterial intima- media thickness（ IMT） in elderly griop（ 56.87% ）was significantly higher than that in control group（29.12% ） （ P 〈 0.01 ）. The increase of IMT showed segmentary in two group, while 42.5% in elderly group and 40.13% in control group, which sowed non- homogeneous and non- concentic round . There was no significant difference between two groupe; in this aspect. Conclusion： The incidence of LEVD in eldrly patients with T2DM Was thgh.Age,Bp,other big vascular diseases and micro micro vascular diseases were important risk factor for LEVD.