健康人左心室节段与整体功能关系的初步研究

Preliminary study of the normal relationship between regional and global left ventricular function

目的探讨健康人左心室节段与整体功能的关系。方法采用实时三维超声心动图测量31例健康志愿者左心室节段与整体容积,从而定量左心室节段与整体功能的关系。结果30例健康志愿者获得了满意的左心室整体及节段容积-时间曲线;各节段室壁对整体收缩及舒张功能的贡献从基底段到心尖段逐渐减低;从心尖帽、前壁、室间隔、侧壁到下壁,室壁对整体收缩功能的作用逐渐增强;从心尖帽、前壁、室间隔、下壁到侧壁,室壁对整体舒张功能的作用逐渐增强。结论健康人左心室节段对整体功能的作用不一致,存在异质性。

Objective To discuss the normal relationship between regional and global left ventricular function. Methods Tne regional and global volumes and functions were investigated by real- time three- dimensional echocardiography in 31 healthy volunteers without cardiovascular diseases. Results RT- 3DE datasets with ideal global and regional volume- time curves were acquired in 30 volunteers. Seventeen segments had significant difference in contribution to the global left ventricular function, which increased from apical to basal segment gradually （ P 〈0.05）. The contribution to global systolic function increased from apex, anterior wall, interventricular septum, lateral wall to inferior wail（ P 〈 0.05） and the contribution to global diastolic function increased from apex, anterior wall, interventricular septum, inferior wall to lateral wall（ P 〈 0.05）. Conclusion The effects of left ventricle segment to global function have heterogeneity.