经颅多普勒超声结合临床特点筛选烟雾病

Transcranial Doppler sonography and clinical feature of screening out moyamoya disease

目的:探讨、交流经颅多普勒(TCD)筛选烟雾病的方法和经验。方法:用TCD筛选出疑似患者,经数字减影血管造影(DSA)或磁共振血管造影(MRA)进一步检查,对确诊患者进行TCD、临床、脑电图及其它影像学特点分析。结果:2004年2月～2005年4月检出可疑烟雾病患者11例,其中6例经DSA或MRA证实。6例均有双侧前循环的狭窄或闭塞。部分患者大脑中动脉供血区可检测到多条低流速、频谱紊乱的血流信号,脑电图有特征性改变;多数患者病史较长、缺少动脉粥样硬化的危险因素。结论:TCD结合临床特点是筛选烟雾病的有效方法。

Objective：To study on method of identifying moyamoya disease by transcranial Doppler sonography （TCD）.Methods：We screened out dubious patients through TCD examination.Dubious patients were diagnosed by digital subtract angiography（DSA）or magnetic resonance angiography（MRA）.Clinical characteristics, examination results of TCD,electroencephalogram and imaging were analyzed.Results：We found out 11 doubtful patients by TCD.Of them six cases were diagnosed by DSA or MRA.AII six patients had bilateral anterior circulation occlusive lesions.TCD of 2 cases showed many vessels with low blood velocity and spectral turbulence at middle cerebral artery district.EEG had special changes.Conclusion：TCD combined with clinical features are effective method of screening out moyamoya disease.