元宝草酮成分的研究

Study on Xanthones from Hypericum samponii Hance

目的对元宝草的化学成分进行研究。方法利用硅胶、聚酰胺、Sephadex LH-20和大孔树脂柱色谱对化合物进行分离,并用光谱方法进行结构鉴定。结果分离鉴定了4个酮类成分:1-羟基-7-甲氧基酮(Ⅰ)、1,3,5-三羟基酮(Ⅱ)、1,3,6,7-四羟基酮(Ⅲ)和芒果苷(Ⅳ)。结论除化合物Ⅳ外,均为首次从该植物中分离得到。

OBJECTIVE To study the chemical constituents of Hypericum sampsonii Hance. METHODS The compounds were isolated by silica gel, polyamide, sephadex LH - 20 and macroreticular resin, and the structures were elucidated by UV, IR, MS,^1 H- NMR, 13 C-NMR and their physicochemical properties, RESULTS Four xanthone compounds were isolated from the aerial parts and identified as 1-hydroxy-7-methoxyxantone （ Ⅰ ）, 1,3,5-trihydroxyxanthone （ Ⅱ ）, 1,3,6,7-tetrahydroxy-xanthone （Ⅲ） and mangiferin （Ⅳ）. CONCLUSION All these compounds are obtained from this plant for the first time except for the compound Ⅳ.