微生物生活周期中的一个新的时期——长期稳定期

A New Phase of Bacteria Life Cycle:Long-term Stationary Phase

传统的对微生物生长时期的认识一般分为4个时期:迟缓期、对数期、稳定期、死亡期。实际上,这种划分不足以使我们认识到微生物生长过程的全貌。近年来许多研究表明,在死亡期之后存在一个完全不同意义的时期——长期稳定期。这个时期可能与微生物在环境中的生存状态更加相似。微生物细胞通过突变得以生存,并在选择中形成稳定期生长优势表型,深入研究微生物长期稳定期具有极其重要的意义。

The traditional view of bacterial life cycle consists of four phases, namely, lag phase, exponential or logarithmic phase, stationary phase and death phase. Although the standard textbook description of the bacterial life cycle has been useful, might not always provide us the whole visage of bacteria growth process. Recently, it has demonstrated that bacterial life cycle is expanded to five phases. It is a significant different growth phase after death phase ： long-term stationary phase, which may be more akin to the nature environment in which microorganisms exist. Microbial cells survive due to mutating, and forming growth advantage during stationary phase （GASP） phenotype in this phase. It is very important for further study the microorganisms in this phase.