2型糖尿病合并高血压对血脂的影响

The effect of diabetes with hypertension on lipid metabolism

目的探讨2型糖尿病合并高血压对脂质代谢的影响。方法将172例门诊2型糖尿病患者，按是否合并高血压分为糖尿病合并高血压组和单纯糖尿病组，每组86例。对各组间血脂水平进行统计学分析。结果两组间血脂水平差异有统计学意义，糖尿病合并高血压组总胆固醇[（5．41±0.13）mmol／L]、甘油三酯[（3.41±0．37）mmol／L]、低密度脂蛋白[（4．11±0．13）mmol／L]明显高于单纯糖尿病组[分别为（4．95±0.11）mmol／L、（2．11±0．20）mmol／L、（3．74±0．12）mmol／L]；高密度脂蛋白两组间差异无统计学意义。结论2型糖尿病合并高血压可发生脂质代谢紊乱。

Objective To investigate the influence of the diabetes with hypertension on lipid metabolism. Methods 172 diabetic outpatients were divided into hypertension group（ n = 86） and non-hypertension group（ n = 86）. The levels of plasma lipid were measured and statistically analyzed. Results Compared with non-hypertension group, in hypertension group the plasma levels of lipid（TC, TG, LDL） significantly increased（ P 〈 0.05） except HDL（P 〉 0.05）. Conclusion Hyperglycemia and hypertension may cause more disorder in the lipid metabolism.