摘要
目的研究高脂血症与糖尿病酮症酸中毒(DKA)并发急性胰腺炎(AP)的关系。方法DKA患者75例,按是否并发AP分为病例组(DKA-AP)和对照组(DKA-NAP),观察两组禁食12h后的血糖、动脉血pH值和血清甘油三酯(TG)水平,并进行比较。结果与DKA-NAP组相比,DKA-AP组的动脉血pH值明显降低(P〈0.05);4例DKA-AP患者的TG呈现一过性明显升高(TG≥11.3mmol/L,P〈0.05),并随着DKA的缓解而下降(TG〈5.65mmol/L)。结论高脂血症(TG≥11.3mmol/L)可能是DKA时并发急性胰腺炎的原因之一。
Objective To study the effect of hyperlipidemia in diabetic ketoacidosis(DKA) with acute pancreatitis(AP). Methods 75 patients admitted with a diagnosis of DKA were divided into the DKA with coexisting AP(DKA-AP) group and the DKA without AP(DKA-NAP) group. Serum glucose,arterial blood gas estimation and serum triglyceride levels were collected and performed with statistical analysis. Results Compared with the DKA- NAP group,the mean pH value of DKA-AP group was lower(7.14 vs 7.29, P〈 0.05). The marked elevation of serum triglycerides (TG ≥ 11.3mmol/L, P 〈 0.05 ) was transient in 4 DKA-AP patients and resolved ( TG 〈 5.65mmol/L) once the episode of DKA was corrected. Conclusion The pathogenesis of AP in DKA varies, but at least in some transient and profound hyperlipidemia is an identifiable factor.
出处
《中国基层医药》
CAS
2007年第3期409-410,共2页
Chinese Journal of Primary Medicine and Pharmacy