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血管造影下甲氨蝶呤栓塞治疗子宫腺肌病

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摘要 目的探讨血管数字减影术(DSA)下经导管甲氨蝶呤(methotrexate,MTX)子宫动脉灌注栓塞治疗子宫腺肌病的临床疗效及不良反应。方法选择33例经B超确诊为子宫腺肌病的患者,用Selding's方法完成子宫动脉超选择性插管,造影证实后用MTX 50mg灌注,并加用新鲜明胶海绵颗粒(直径1~3mm)栓塞:术后观察MTX药物灌注子宫动脉栓塞前后患者月经量、痛经程度、子宫体积及性激素水平等的变化。结果MTX灌注子宫动脉栓塞术无不良反应;经治疗的33例,插管栓塞成功率100%,月经量减少,痛经疼痛程度减轻,子宫体积明显缩小。结论微创介入技术和药物相结合治疗子宫腺肌病,不良反应少,疗效确切,为临床提供了一种新的治疗途径。
出处 《中国基层医药》 CAS 2007年第3期461-462,共2页 Chinese Journal of Primary Medicine and Pharmacy
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