血尿酸水平与冠状动脉病变程度的相关性探讨

Correlation between uric acid level and severity of coronary artery disease

目的:了解血尿酸水平与冠状动脉病变程度的关系。方法:79例病人行冠状动脉造影以了解冠脉的病变程度,同时检查空腹血尿酸水平。结果:冠脉造影显示冠脉正常者27例,冠心病52例。较之冠脉正常组血尿酸水平[(334±82)μmol/L],冠脉单支病变组血尿酸水平[(349±89)μmol/L],冠脉双支病变组血尿酸水平[(372±85)μmol/L],冠脉三支病变组血尿酸水平[(396±91)μmol/L]均显著升高(P<0.05),而且冠脉病变三组间血尿酸水平两两相比均有显著差异(P<0.05)。结论:随着血尿酸水平升高,冠状动脉病变程度增加。

Objective： To study the correlation between uric acid level and severity of coronary artery disease. Methods：The coronary angiography was performed and blood uric acid level was detected in 79 patients. Results： The coronary angiography shows that there was normal in 27 persons and 52 patients were suffered from coronary artery disease. Compared with uric acid level of normal control group [（334±82）μmol/L], the uric acid level of one branch, two branches, three branches of coronary artery significantly increased （P〈0.05 all）, and respectively was E （349±89）μmol/L]. ,[372±85）μmol/L]. [ （396±91）μmol/L]. The uric acid level progressively increased （P〈0. 05 all） when compared each other among three groups of coronary artery disease. Conclusion： There is correlation between uric acid level and severity of coronary artery disease. Following the uric acid level increase, the severity of coronary artery disease increase.