摘要
根据血竭中游离黄酮存在着酸性差异,采用溶剂除杂,转溶于乙醚,再用pH梯度萃取得到不同酸性的黄酮,进而对弱酸性组分分离纯化得到2个单体化合物.通过考察不同提取部位对-αD-葡萄糖苷酶抑制活性的变化,发现弱酸性成分的活性较强,比血竭全粉提高45.5%,为研究龙血竭中黄酮类化合物对-αD-葡萄糖苷酶的抑制作用提供依据.
According to different acidity of free Flavonoids in Resina Draconis, different acidic lavonoids were extracted with the pH gradient extraction method from ethyl ether. Two compounds were isolated from weak acidicmixture. Weak acidic compounds showed higher activity in comparing to the crude powder of Guangxi Resina Draconis with 45.5 % increase of IC50. This provides a useful reference to the study of inhibitive activity of flavones for α-D-glucosidase enzyme.
出处
《上海大学学报（自然科学版）》
CAS
CSCD
北大核心
2007年第2期212-215,共4页
Journal of Shanghai University:Natural Science Edition
基金
上海市科技发展基金资助项目(02DZ9118)
