原发灶不明的颈部转移癌28例临床分析

Analysis of 28 cervical lymph nodal metastases of unknown primary sites

目的:探讨原发灶不明的颈部转移癌的诊断、原发灶不明的原因及治疗。方法:回顾分析1990年1月～2005年12月我院收治的28例原发灶不明的颈部转移癌的临床资料。结果:中上颈低分化转移鳞癌宜选用放疗,转移性鳞癌则采用手术加放疗,转移性乳头状腺癌的治疗采用甲状腺癌联合根治术。本组总的5年生存率分别96.4%、78.6%、50.0%。结论:对颈部原发灶不明的颈部转移癌应加强认识,治疗上应根据病理类型、部位、局部和全身情况进行综合考虑。

Objective ：To explore the diagnosis ,reason and treatment of cervical lymph nodal metastases of unkown primary sites. Methods：The clinical data in 28 patients with cervical nodal metastases of unkown primary sites were retrospectively analyzed.Results： For metastatic masses of the upper or middle part of the neck,pooly-differentiated carcinoma was treated with radiotherapy,squamous-cell carcinoma was treated with radiotherapy plus surgery, while papillary adenocarcinoma was treated by combined radical thyroidectomy.1-,3-,5-year survival rate was 96.4% ,78.6% ,50.0% respectively.Conclusion：The diagnosis of cervical nodal metastasis of unknown primary sites is signifficant, the management should be given according to the location of lymph node involved and histopathologic type of the tumor.