盐酸二甲胺四环素软膏治疗急性局限性冠周炎疗效观察

Application of Minocycline Hydrochloride Ointment on the Treatment of Wisdom Tooth Pericoronitis

目的评价盐酸二甲胺四环素软膏治疗急性局限性冠周炎的临床疗效。方法将急性局限性冠周炎92个患牙随机分成两组,在常规冠周冲洗后分别用盐酸二甲胺四环素软膏和碘甘油置冠周盲袋内治疗。结果用药5d后,软膏组治疗效果优于碘甘油组(P<0.01)。结论盐酸二甲胺四环素软膏对急性冠周炎的治疗效果显著,具有疗效确切,减少患者就诊次数等优点。

Objective To evaluate the effectiveness of minocycline hydrochloride ointment and iodine glycerine on the treatment of wisdom tooth pericoronitis. Methods Ninety-two acute pericoronitis cases were included in this study. These cases were divided into two groups in random. After routine pocket rinsing,minocycline hydrochloride ointment or iodine glycerine were applied locally into the pocket. Results After 5 days, Minocycline Hydrochloride Ointment appeared more effective than iodine glycerine（P〈0.01）. Conclusion Minocycline Hydrochloride Ointment used locally is more effective than iodine glycerine in the treatment of acute pericoronitis. And this method can reduce the frequency of going to hospital by patients.