1684株结核分支杆菌单一、联合药敏试验结果分析

Analysis on Single and Multiple Drug Sensitivity Test Result of 1,684 Mycobacterium Tuberculosis

目的了解长沙市结核分支杆菌耐药情况。方法采用绝对浓度法进行结核分支杆菌药敏试验。结果1 684株结核分支杆菌药敏试验显示:单一药敏试验耐药率高低次序是:RFT(15.50%)、SM(12.59%)、RFP(10.69%)、INH(8.37%)、PZA(6.47%)、PAS(2.79%)、EMB(2.32%)、KM(1.72%);总耐药率为26.03%。结论长沙市结核分支杆菌总的耐药率低于全国平均水平。

Objective To investigate the status of drug- resistance of Mycobacterium tuberculosis in Changsha City. Methods The drug sensitivity of Mycobacterium tuberculosis was measured by absolute concentration. Results The drug sensitivity tests of 1,684 strains of Mycobacterium tuberculosis showed that the highest rate of single drug resistance was RFT （1.5..50%）, followed by SM（12..59%）, RFP（10.69%）, INH（8.37%）, PZA（6.47%）, PAS（2.79%）, EMB（2,32%）, and KM（1. 72 % ）and the total drug resistance rate was 26.03 %. Conclusion The total Mycobacterium tuberculosis drug resistance rate in Changsha City is below the national average level.