摘要
目的:建立糖脂益片的质量标准。方法:采用薄层色谱法定性鉴别糖脂益片中黄芪、黄连、山楂,采用高效液相色谱法(HPLC)测定糖脂益片中盐酸小檗碱含量。结果:薄层色谱法可检出黄芪、黄连、山楂,盐酸小檗碱在0.00624-0.03120mg/ml浓度范围内线性关系良好,r=0.9992,平均加样回收率为98.89%。结论:薄层色谱鉴别方法和HPLC法简便,易于操作,重现性好,结果稳定,可有效控制糖脂益片的质量。
Objective: To establish quality control of Tangzhiyi tablets. Methods: astraglionych, coptidis rhizoma, chinese hawthorn were identified by thin layer chromatograph (TLC). The contents of berberine hydrochloride were determined by high performance liquid chromatograph (HPLC). Results: Astraglionych, coptidis rhizoma, and Chinese hawthorn could be indentified by TLC, berberine hydrochloride showed a good linear relationship at a range of 0. 006 24-0. 031 20 mg/ml, r =0. 999 2, The average recovery rate was 98. 89%. Conclusion: The methods are accurate and reliable, and can be used for the quality control of Tangzhiyi tablets effectively.
出处
《新疆医科大学学报》
CAS
2007年第2期112-114,共3页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区科技攻关和重点科技项目(200233106)