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血管生成素与子宫内膜病生理变化的研究现状 被引量:1

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摘要 近年研究血管生成素(Angiopoietin,Ang)及其受体(Tie-2)系统是调控血管完整性的重要因子,参与子宫内膜生理性及病理性血管生成。正常月经周期中,Ang-1在子宫内膜的分泌期表达升高,可能对排卵后期子宫内膜血管发育,尤其对哺乳动物子宫内膜螺旋动脉的生长具有重要作用。在功能失调性子宫出血、子宫内膜异位症、子宫内膜癌等病变中,Ang及Tie-2的表达发生变化,可能促进了异常子宫内膜血管生成,从而促进其病理发生过程。
出处 《国外医学(妇产科学分册)》 2007年第2期83-86,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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同被引文献3

  • 1Blurnenthal RD, Taylor AP, Goldman L, et al. Abnormal expression of the art-giopoietins and Tie receptors in menorrhagic endometrium [ J ]. Fertil Steril, 2002,78(6):1 294-1 300.
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