高压氧综合治疗持续植物状态30例疗效分析

Effect of hyperbaric oxygen combined therapy on persistent vegetative state in 30 patients

目的评估高压氧综合治疗持续植物状态的疗效和探讨最佳治疗方案。方法回顾性分析了1999年—2005年应用高压氧治疗的30例持续植物状态病例，主要分析了原发病因、高压氧治疗次数以及高压氧治疗时机与疗效的关系。结果脑外伤组显效率和好转率明显高于非脑外伤组（P〈0．05），开始治疗时间≤30d组及31～60d组好转率明显高于≥61d组（P〈0．05）。结论高压氧综合治疗对脑外伤所致持续植物状态患者60d以内开始行高压氧治疗的患者疗效较好。

Objective To evaluate effectiveness of hyperbaric oxygen combined therapyon persistent vegetative state and explore the best therapeutic regimen for it. Methods Thirty cases of persistent vegetative state treated with hyperbaric oxygen combined therapy from 1999 to 2005 were analyzed retrospectively, including the effects of etiological factors and treatment times and treatment juncture on therapy. Results The excellence rate and the improvement rate were significantly higher in cerebral trauma group than those in no cerebral trauma group. And two groups in which the patients began to receive treatment when became persistent vegetative state for less 61 days recovered better than the other one in which the patients began to receive treatment when became persistent vegetative state for more 60 days. Conclusion The effectiveness of hyperbaric oxygen on the patients with persistent vegetative state caused by cerebral trauma and the patients who just begin to receive hyperbaric oxygen treatment when having been ill for less 61 days is better.