眩晕中医分型的血液流变性和血脂血糖变化

Hemorheology and serum lipid and sugar changes in vertigo of different traditional Chinese medical types

目的:观察眩晕中医分型的血液流变性、血脂和血糖的变化.方法:将434例眩晕患者分为肝阳上亢、痰浊中阻、肾精不足、气血亏虚4型,观察不同中医分型的眩晕患者的血液流变性、血脂和血糖的变化.结果:肝阳上亢、痰浊中阻、肾精不足型眩晕患者全血粘度、血沉、纤维蛋白原、血栓干重、甘油三酯和血糖等指标升高,血清高密度脂蛋白胆固醇则降低(P<0.05),痰浊中阻型患者的红细胞压积、血清总胆固醇升高(P<0.05);而气血亏虚型患者RBC压积降低,血沉增快(P<0.05).各型之间尤以痰浊中阻型患者的全血粘度与RBC压积增加较其它各型有统计学意义(P<0.05);肾精不足型患者血糖增加有统计学意义(P<0.05);气血亏虚型患者全血粘度与RBC压积降低、血沉增快有统计学意义(P<0.05).结论:眩晕患者与正常人的血液流变性、血脂和血糖水平呈现统计学差异,不同中医分型眩晕患者的上述指标亦有所不同.

AIM： To observe the hemorheology, serum lipid and sugar changes in vertigo patients of 4 different traditional Chinese medical （TCM） types based on different symptoms and signs. METHODS： Totally 434 vertigo cases were divided into 4 TCM types： the liver yang ascension （ LYA）, the internal retention of phlegm and dampness （IROPAD）, the insufficiency of kidney essence （IOKE）, and the qi and blood deficiency （QABD）. The hemorheology, serum lipid and sugar changes of the above types were observed. RESULTS： In the LYA, IROPAD and QABD patients, whole blood viscosity, ESR, Hot, fibrinogen, dry weight of thrombus, triglyceride and serum sugar levels were significantly higher than those of the normal people （ P 〈 0.05 ）, but serum level of high-density lipoprotein cholesterol was significantly lower than that of the normal （ P 〈 0.05 ）. The QABD patients showed obviously decreased Hct and increased ESR （ P 〈 0.05 ）. Compared with the other types, whole blood viscosity and Hot of the IROPAD patients increased significantly （ P 〈 0.05 ） ; the IOKE patients showed obviously increased serum sugar （P 〈 0.05） ; whole blood viscosity and Hct in the QABD patients decreased, but their ESR increased （ P 〈 0.05 ）. CONCLUSION： There are statistical differences in hemorheology, serum lipid and sugar level between vertigo patients and normal people. The changes in the above indexes are different in the 4 TCM types of vertigo patients.