摘要
干燥综合征(Sjogren’s Syndrome,SS)是一种以侵犯唾液腺和泪腺等外分泌腺、具有高度淋巴细胞浸润为特征的系统性自身免疫病。口、眼干燥为常见的症状,常出现皮肤、肺、肝、肾、神经及血管等多系统损害。本病分为原发性(pSS)和继发性两类。本文重点介绍了pSS的发病机制、病理改变、临床表现、实验室检查、诊断标准及治疗最新进展。
Sjogren's syndrome is a chronic autoimmune disorder, characterized by lymphocytic infiltration and malfunction of the exocrine glands, resulting in dry mouth and eyes. The syndrome can present either alone ( primary Sjogren's syndrome ) or secondary to an underlying connective tissue disease ( secondary Sjogren's syndrome ). Systemic impairments, resulting from cutaneous, respiratory, hepatic, renal, neurologic, and vascular involvement, often occur. This article emphatically introduces the pathogenesis, pathologic changes, clinic manifestation, laboratory examination, diagnostic standard, latest treatment progress of primary Sjogren's syndrome.
出处
《实用医院临床杂志》
2007年第3期6-8,共3页
Practical Journal of Clinical Medicine