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非霍奇金淋巴瘤中的人类疱疹病毒-6型 被引量:1

Detection of herpesvirus type 6 (HHV6) in non-Hodgkin’s lymphomas
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摘要 人类疱疹病毒-6型(HHV-6)与多种肿瘤有关。本实验为了探讨HHV-6与非霍奇金淋巴瘤(NHL)的关系,用聚合酶链反应(PCR),液相同位素杂交和免疫组化检测20例NHL。结果显示有12例病例组织中含HHV-6,占60%。10例P53蛋白异常(50%)。提示HHV-6与NHL有关系。 The Human Herpesvirus 6 (HHV - 6) has a relation with many tumours, We want to study the relation between HHV - 6 and non- Hodgkin' s lymphomas. The Polymerase Chain Reaction, Liquid hybridization and Immunohistochemical staining were used to test the 20 cases of non - Hodgkin' s lymphomas. HHV6 was detected in 12 cases (60%). In addition, abnormal P53 proteine have been detected in 10 eases ( 50% ). It shows that HHV - 6 is involved in non - Hodgkin' s lymphomas.
出处 《医学研究杂志》 2007年第4期82-84,共3页 Journal of Medical Research
基金 北京协和医院院科研基金资助
关键词 人类疱疹病毒-6型 P53 非霍奇金淋巴瘤 Human Herpesvirus 6 P53 non - Hodgkin' s lymphoma
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